Scientists have discovered mushrooms that can stop cancer and prolong life

In recent decades, medicine has made huge strides forward in the search for effective cancer treatments. And one of the most exciting recent discoveries is that mushrooms may have a beneficial effect on the process of cancer cell division. A recent study by scientists from Japan has revealed the potential properties of mushrooms to stop cancer cells from multiplying.

Specialists explain that active substances contained in coralline mushrooms affect the mechanisms of cell division, preventing them from functioning normally. They are also able to inhibit the growth of new blood vessels, which are necessary to feed the tumor. This makes mushrooms a potentially valuable tool in the fight against cancer.

Mushrooms, through a special type of cell division, can prevent cancer from developing and live a very long time. Scientists at Wageningen University & Research have found that some species of long-lived mushrooms use a mechanism called “clamp junction” to stop cell mutations and reduce the likelihood of cancer development.

Fungi are made up of networks of filaments called mycelium. The cells of these filaments contain nuclei with half a set of chromosomes, known as “haploid” nuclei. When the fungus needs to produce spores to reproduce, these nuclei fuse together. However, mutations can occur in these nuclei that interfere with the fusion of the mycelium filaments and the fungus’ ability to reproduce asexually.

These mutations essentially represent the fungal parallel to cancer in humans and plants. They rob their host for their own uncontrolled growth. Researchers call them “nuclear cancers.” However, some fungi have the ability to avoid these mutations and live for a very long time.

Researchers have found that these fungi use a special type of cell division called “clamp fusion” to prevent harmful mutations from accumulating. This process involves storing the nuclei in a separate compartment to check their genetic quality before fusion. If the nuclei contain mutations, they cannot fuse, leading to a dead end for the cell and the end of its nucleus.

Scientists hypothesize that the clamping junction is a test point for one of the haploid nuclei. Loss of the ability to fuse is a major pathway to nucleus cancer, so this mechanism acts as a screening device for nucleus quality. The two nuclei constantly test each other for fusion ability, and nuclei with mutations in fusion genes fail. This allows fungi to have a constant and low risk of core cancer, regardless of their size or lifespan.

This mechanism is only found in long-lived species of fungi, since short-lived species do not need to prevent cancer development. This is another example of evolutionary mechanisms that allow organisms to avoid the accumulation of cancerous mutations and live long lives.

The study of fungal core cancer is an important step in understanding the processes of cancer development and may help in the development of new methods of treatment and prevention of this disease.

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