The largest study confirmed the benefits of coffee for health

Coffee is one of the most popular beverages: the world’s total consumption is about 2.25 billion cups a day. The high prevalence of caffeinated preparations causes interest in their side effects. Past observations have shown that coffee can reduce the risk of many diseases, in particular liver and prostate cancer, caries, and also stimulate erection and cognitive abilities. The least clear is how coffee affects longevity. In 2015, Japanese scientists came to the conclusion that, under certain conditions, it helps prevent early mortality. The conclusion was made on the basis of a survey of about 90 thousand people.
Similar work was carried out earlier, but often the revealed correlation did not have a strong statistical significance, and the number of respondents was estimated at tens of thousands. To improve the reliability of the results, experts from the International Agency for Research on Cancer (IARC), Imperial College London, Oxford University and other institutions used the data of a longitudinal study EPIC. The final sample included 451,743 people aged 35 and over who were involved in 1992-2000. They represented the ten countries of Europe: Germany, Denmark, Italy, Greece, France, Norway, Netherlands, Spain, Britain and Sweden.
In the course of observations that lasted for 16 years, the respondents reported a positive diagnosis of cancer (22,537 people), cardiovascular diseases (12,619 people) and other pathologies. Health status and mortality were compared with levels of education and physical activity, smoking and diet, including alcohol and coffee consumption. In addition to self-reports, the scientists used the results of biochemical tests, for example albumin (liver biomarker function) and C-reactive protein (growth indicates inflammation) in a subgroup of participants in the evaluation of the anamnesis. During the work for various reasons, 41 693 volunteers died.
The analysis showed that daily consumption of three or more cups of coffee is significantly associated with a reduction in the risk of death: in men, the drop was 18, for women – 8 percentage points. So, coffee negatively correlated with digestive disorders, reducing their probability by 40 and 59 percentage points in women and men respectively. It is curious that the trend was maintained regardless of the content of caffeine in the drink. At the same time, his abuse was associated with a 30 per cent higher death rate from ovarian cancer. According to the authors, new results confirm that regular moderate consumption of coffee can prevent early mortality.

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